New Step by Step Map For ceesdekker
New Step by Step Map For ceesdekker
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Nanotechnology presents An array of opportunities to contribute to biology. Right here I will present examples in which nanofabrication – the chance to make confined constructions with dimensions at will – is utilised to look at the biophysics of solitary molecules and cells. I'll existing some illustrations from our lab:
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Multicolor imaging from the bacterial nucleoid and mobile division proteins with blue, orange, and in the vicinity of-infrared fluorescent proteins
Our function was swiftly followed up by Other individuals, most notably by Phaedon Avouris and colleagues at IBM, who in October 1998 released their conclusions on transistors constructed from one- and multi-walled carbon nanotubes in Used Physics Letters.
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial cell division; and first ever analyze on the dynamics DNA supercoils and the invention of supercoil hopping
Experimental phase diagram of negatively supercoiled DNA calculated by magnetic tweezers and fluorescence,
MATLAB codes for information processing are offered at . Julia codes utilized for numerical simulation are available at .
Atomic pressure microscopy reveals that vaccinia topoisomerase IB generates filaments on DNA inside a cooperative vogue
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At the moment, we also realized that it should be possible to employ only one semiconducting carbon nanotube to help make a transistor — and we established out to make it. We stretched personal semiconducting nanotubes across metallic electrodes and employed the underlying silicon substrate as a gate electrode, creating The essential 3-terminal layout of a industry-influence transistor (Fig.
Since 2000 he moved to one-molecule biophysics and nanobiology, with analysis from studies of DNA loop extrusion and supercoiling to DNA translocation by nanopores. Much more recently his investigation has focused on researching chromatin construction and mobile division with germs on chip, though he can be attempting to in the long run Develop artificial cells from the bottom up.
Nanoscientist Cees Dekker is definitely an amiable and flamboyant man who seems Substantially youthful compared to 62 years he basically is – modern glasses, psychedelic shirt, engaging smile – but not a person to squander https://www.ceesdekker.net time. He will take his time, but no more than vital.
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Case in point (2) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in gray, the rim from the pore is highlighted in pink, as well as a 3D rendering from the movement from the DNA rod is shown.